DNA methylation as predictive marker of response to immunotherapy?
نویسندگان
چکیده
منابع مشابه
RIPK3—a predictive marker for personalized immunotherapy?
Cancer immunotherapy is an attractive therapeutic option but it is currently unclear which patient may benefit from such approaches. Using the model of cervical cancer, we have demonstrated that PolyIC-driven immunogenicity strictly depends on the necroptosis regulator RIPK3 in the neoplastic cells. This proposes RIPK3 as a novel predictive marker for personalization of cancer immunotherapy.
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ژورنال
عنوان ژورنال: memo - Magazine of European Medical Oncology
سال: 2021
ISSN: 1865-5041,1865-5076
DOI: 10.1007/s12254-021-00696-3